Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel

• Status: Unknown status
• Trial end date: 2009-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The project is a study comparing the effectiveness of two topical anesthetics for control of pain associated with dental needle insertion in the palatal mucosa. A standard dental topical anesthetic (20% benzocaine) will serve as an "active" control and will be compared to a combination topical anesthetic, consisting of 20% lidocaine, 4% tetracaine and 2% phenylephrine (TAC Alternate Gel, Compounding Arts Pharmacy, Lafayette, LA).

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The University of Texas Health Science Center, Houston
• Treatments: Anesthetics; Benzocaine; Lidocaine; Phenylephrine; Tetracaine

Criteria

Inclusion Criteria:

1. Volunteers 18 years or older

2. Ability to consent to participate in the research

3. Ability to communicate a VAS score

4. Generally healthy, ASA I and ASA II

5. No known drug allergies

6. Ability to tolerate pulse oximeter and blood pressure cuff without psychological, or physiological consequence

Exclusion Criteria:

1. Allergy or other contraindications to the topical anesthetics

2. Inability to consent to participation in the study

3. Use of analgesics prior to the procedure

4. Vulnerable populations