Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis

• Status: Completed
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to evaluate the performance of two toothpastes in controlling established gingivitis and dental plaque in adults.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Colgate Palmolive
• Treatments: Fluorides; Triclosan

Criteria

Inclusion Criteria:

• Availability for the six-month duration of the study.

• Good general health.

• Minimum of 20 uncrowned permanent natural teeth (excluding third molars).

• Initial gingivitis index of at least 1.0 as determined by the use of the Loe and Silness Gingival Index.

• Initial plaque index of at least 1.5 as determined by the use of the Quigley and Hein Plaque Index (Turesky Modification).

• Signed Informed Consent Form.

Exclusion Criteria:

• Presence of orthodontic bands.

• Presence of partial removable dentures.

• Tumor(s) of the soft or hard tissues of the oral cavity.

• Advanced periodontal disease (purulent exudate,tooth mobility, and/or extensive loss of

• periodontal attachment or alveolar bone).

• Five or more carious lesions requiring immediate restorative treatment.

• Use of antibiotics any time during the one month prior to entry into the study.

• Participation in any other clinical study or test panel within the one month prior to entry

• into the study.

• Pregnant women or women who are breast feeding.

• Receive a dental prophylaxis in the past two weeks prior to baseline examinations.

• History of allergic to personal care/consumer products or their ingredients.

• Taking any prescription medicines. That might interfere with the study outcome.

• Individuals with an existing medical condition which prohibits them from not eating or drinking for periods up to 4 hours.