Comparative Study Between Febuxostat Versus Vitamin E in Non-alcoholic Steatohepatitis Patients With Hyperuricemia
Status:
Recruiting
Trial end date:
2024-02-25
Target enrollment:
Participant gender:
Summary
This study aims at evaluating and comparing the protective outcomes of using Febuxostat
versus Vitamin E in Hyperuricemia non-alcoholic steatohepatitis patients without cirrhosis.
The intervention is 6-months duration and the study will assess the efficacy of either drug
as fibrosis improvement (≥ 1 stage) with no worsening of NASH or NASH resolution with no
worsening of fibrosis with the study considered successful if either 1ry end point is met.
Also, assessment of biochemical markers related to steatosis, inflammation, oxidative stress,
insulin resistance and liver fibrosis will be done.