Comparative Study Between Hydrocortisone and Mannitol in Treatment of Postdural Puncture Headache
Status:
Completed
Trial end date:
2015-11-01
Target enrollment:
Participant gender:
Summary
Fifty patients of both sex, aged 18-50 years and ASA I and II undergoing elective lower
abdominal and pelvic surgery under spinal anesthesia were included in this randomized
double-blind study. Patients were randomly divided into 2 groups 25 each; group (I) received
intravenous hydrocortisone 100mg every 8 hours for 48 hours and group (II) received
intravenous infusion of mannitol 20% 100ml over 30 minutes followed by 100ml every 12hours.
Mean (+/- SD) of headache intensity at 0, 6, 12, 24 and 48 hours after beginning of treatment
was assessed using visual analog scale.