Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate

• Status: Completed
• Trial end date: 2020-11-10
• Target enrollment: 0
• Participant gender: Female

Summary

Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate, Pre-operative Administration.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Egymedicalpedia
• Collaborator: ALAZHAR UNIVERSITY
• Treatments: Ethamsylate; Oxytocin; Tranexamic Acid

Criteria

Inclusion Criteria:

1. Pregnant females admitted for elective Cesarean Section.

2. Gestational age (38 to 41 weeks).

3. Age of the participants: 20 to 40 years.

4. Body Mass Index (18.5 - 29.9).

5. Singleton living fetus.

6. No medical disorders.

7. Informed written consent from the candidates.

Exclusion criteria:

1. - Medical and surgical disorders as thyroid dysfunction, which was excluded by routine thyroid function test (free T3, free T4, and thyroid-stimulating hormone(TSH), all of them should be within normal limits).

2. -Bleeding tendency, was excluded by platelet count, coagulation time, bleeding time, prothrombin time, partial thromboplastin time, and thrombin time (all should be within normal).

3. -Acute and chronic liver or kidney diseases; blood disorders, such as anemia.

4. -Allergy to Tranexamic acid or any drug used.

5. -Risk factors for PPH, such as polyhydramnios, fetal macrosomia, antepartum hemorrhage.

6. - Abnormal placentae such as placenta previa and placental abruption.

7. -Pregnancy complications such as severe pre-eclampsia, Gestational HTN, Gestational DM, and multi Fetal pregnancies, those requiring blood transfusion.

8. - Patients who refused spinal anesthesia.