Comparative Study Between Two Adjuvant Drugs to Bupivacaine for Post-operative Epidural Analgesia in Abdominal Surgeries

• Status: Recruiting
• Trial end date: 2022-07-31
• Target enrollment: 0
• Participant gender: All

Summary

Epidural analgesia is associated with early postoperative mobilization and rehabilitation with minimally associated pain and discomfort. Analgesic effect of local anesthetics can be augmented by addition of adjuvants in epidural anesthesia ensuring satisfactory postoperative period. This study evaluates the effect of dexmedetomidine and fentanyl as additives to bupivacaine for epidural analgesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Ain Shams University
• Treatments: Analgesics; Bupivacaine; Dexmedetomidine; Fentanyl

Criteria

Inclusion Criteria:

• ASA I or ASA II patients.

• Age group: 21-70 years old.

• BMI ≤40

• Duration of procedure ≤ 180 minutes.

Exclusion Criteria:

• Patients with known neurologic and psychiatric illness will be excluded from the study.

• Contraindications for epidural anesthesia as patient refusal, bleeding or coagulation test abnormalities, local skin infection at spinal lumbar region, raised intracranial pressure and hypovolemia

• Spine abnormalities.

• Systemic disorders like hematological, respiratory, cardiac, renal or hepatic insufficiency.

• Allergy to any of the drugs used in the study.