Comparative Study of Ceftaroline vs. Ceftriaxone in Adult Subjects With Community-Acquired Pneumonia

• Status: Completed
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether ceftaroline is effective and safe in the treatment of Community-Acquired Pneumonia

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Forest Laboratories
• Treatments: Ceftaroline fosamil; Ceftriaxone; Cephalosporins; Clarithromycin

Criteria

Inclusion Criteria:

Subjects are required to meet the following inclusion criteria:

• Community-acquired pneumonia

• initial hospitalization, or treatment in an emergency room or urgent care setting

• infection would require initial treatment with IV antimicrobials.

Exclusion Criteria:

Subjects must NOT meet any of the following exclusion criteria:

• CAP suitable for outpatient therapy with an oral antimicrobial agent

• respiratory tract infections not due to community-acquired bacterial

• Non-infectious causes of pulmonary infiltrates

• Pleural empyema

• Infection with an atypical organism

• History of any hypersensitivity or allergic reaction to any ß-lactam antimicrobial

• History of any hypersensitivity or allergic reaction to clarithromycin or any macrolide/ ketolide