Comparative Study of Different Neoadjuvant Therapies Before Radical Hysterectomy in Stage Ib2-IIa2 Cervical Cancer
Status:
Completed
Trial end date:
2015-07-01
Target enrollment:
Participant gender:
Summary
For stage Ib2-IIa2 cervical cancer patients, neoadjuvant therapy followed by radical
hysterectomy and pelvic lymphadenectomy is one of the managements. Post-operative concurrent
chemo-radiotherapy is necessary if the patients have high-risk factors, including positive
surgical margin, parametrium and pelvic nodes. Our previous retrospective study showed that
combination of neoadjuvant chemotherapy and brachytherapy reduced the proportion of
post-operative concurrent chemo-radiotherapy compared to neoadjuvant chemotherapy alone.