Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery
Status:
Completed
Trial end date:
2012-09-01
Target enrollment:
Participant gender:
Summary
Objective: The aim of the present study was to compare hemodynamic changes using 7.5 mg of
midazolam and 10.0 mg of diazepam during the surgical removal of symmetrically positioned
third molars.
Study design: A prospective, randomized, double-blind, clinical trial was carried out
involving 120 patients divided in three groups: Group 1 (diazepam and placebo), Group 2
(midazolam and placebo) and Group 3 (diazepam and midazolam). Each subject underwent two
surgeries on separate occasions under local anesthesia.