Comparative Trial of Standard Versus Low-dose Peg-Interferon Plus Ribavirin in the Treatment of Chronic Hepatitis C

• Status: Completed
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficacy and safety of low-dose interferon-alfa-2b plus ribavirin compared to the standard-dose of the same combination in patients with chronic hepatitis C.

• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kyoto University
• Treatments: Interferon alpha-2; Interferon-alpha; Interferons; Ribavirin

Criteria

Inclusion Criteria:

• Clinical diagnosis of Chronic Hepatitis C. Must be infected with genotype 1b viruses

Exclusion Criteria:

• Hemoglobin levels<8.5g/dL,

• Platelet counts<50,000/mm3,

• Total polymorphonuclear counts<1000/mm3

• Pregnancy,

• Renal dysfunction,