Comparative Validation of the Triptorelin Test for the Diagnosis of CPP in Girls

• Status: Unknown status
• Trial end date: 0000-00-00
• Target enrollment: 40
• Participant gender: Female

Summary

The aim of the study is to determine the specificity, sensitivity and diagnostic efficiency of the Triptorelin Test in the assessment of CPP compared to GnRH test as gold standard.

Hypothesis: Aqueous Triptorelin Acetate is so efficient as GnRH to CPP assessment.

Study population are girls with suspicious clinical features of precocious puberty

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital de Niños R. Gutierrez de Buenos Aires
• Treatments: Triptorelin Pamoate
• Last Updated: 2011-01-14

Criteria

Inclusion Criteria:

• premature thelarche and/or

• accelerated growth velocity (above 90 percentile)

• advanced bone age at least 1.5 year in relation to chronological age.

Exclusion Criteria:

• contact with sources of exogenous estrogens in the last four months previous to evaluation,

• suspicion of peripheral precocious puberty,

• previous central nervous system illness or suspicion of organic central precocious puberty.