Compare Methadone Combined With N-Acetyl-Cysteine (NAC) and Methadone Alone for Opioids Astaining

• Status: Unknown status
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Evaluation whether higher retention rate is in those of combined methadone with N-Acetyl-Cysteine compared to those with methadone alone during a six-month study.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Taichung Veterans General Hospital
• Treatments: Acetylcysteine; Methadone; N-monoacetylcystine

Criteria

Inclusion Criteria:

1. Age between 20-65 years old, all genders.

2. Psychiatry doctor diagnosed who met DSMIV-TR criteria opioid addiction or opioid abusing.

3. Participants need to understand procedures and assays of this experiment.

4. Participants are willing to accept methadone substitutive abstaining program.

5. Participants are willing to provide small amount of blood for testing.

6. Participants are voluntarily to join interview(s), approximately 30-45min.

Exclusion Criteria:

1. Participants have respiratory distress or other respiratory system illnesses.

2. Participants have serious illness and possible die within 1 year or intensive care needed within 6 month.

3. Participants have been diagnosed cardio-vascular disease recently.

4. Participants have allergy to N-acetylcysteine.