Compare Propofol to Fentanyl and Midazolam for Colonoscopy

• Status: Unknown status
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aim is to determine if Propofol or the combination of Fentanyl and low-dose Midazolam, are equivalent for patient satisfaction and discomfort when undergoing a colonoscopy. This is a prospective randomized study of 262. The primary outcome of this study is participant's satisfaction and discomfort of the colonoscopy procedure as perceived by the participant, and the secondary outcome will be the discomfort of the patient and difficulty of the procedure as perceived by the physician.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Saint Joseph Mercy Health System
• Treatments: Fentanyl; Midazolam; Propofol

Criteria

Inclusion Criteria:

• Age > 18

• Elective outpatient colonoscopy

• American Society of Anesthesiology Class (ASA) < IV

Exclusion Criteria:

• Age < 18

• Inpatient status

• Emergency procedure

• History of colonic or rectal resection

• History of hypersensitivity to Propofol (or soy or egg products),Fentanyl or Midazolam

• ASA of IV

• Neurological deficit

• Acute gastrointestinal bleeding

• On anticoagulation agents

• Noncompliance with bowel regiment

• Pregnant women

• Prisoners