Compare Safety and Pharmacokinetic Properties of Surfolase Capsule(Acebrophylline 100mg) and Surfolase CR(200mg)
Status:
Completed
Trial end date:
2013-09-01
Target enrollment:
Participant gender:
Summary
Acebrophylline is metabolized by being separated into Ambroxol and 7-theophylline when orally
administered as a salt composed of an acid-base as a compound that was synthesized by and
chloride (salifying) the ambroxol to 7-theophylline. Acebrophylline is selectively applied to
the bronchial or lung tissue and inhibit the activity of phospholipase bronchoalveolar shows
the expectorant action to raise the surface activity of the alveolar, leukotrienes (LTs) and
by suppressing the production of prostaglandins (PGs), showed potent anti-inflammatory
activity, bronchial was celebrated by reducing the bronchial hyperreactivity to normal state
is allowed to recuperate or extended.
It was developed to improve compliance improve pharmaceutically Surfolase
capsule(Acebrophylline 100mg) that intake twice daily 100mg to Surfolase CR(Acebrophylline
200mg) that intake once daily 200mg