Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice

• Status: Completed
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Tick borne diseases are increasing in Norway. Lyme borreliosis is the most common infection. Erythema migrans is mainly diagnosed and treated in general practice. There is disagreement about what antibiotic treatment that should be given. An RCT with the three most common antibiotics used, will support data for revision of national guidelines.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Morten Lindbaek
• Collaborators: Norwegian Institute of Public Health; Norwegian University of Life Sciences; Sorlandet Hospital HF
• Treatments: Amoxicillin; Anti-Bacterial Agents; Doxycycline; Penicillin V

Criteria

Inclusion Criteria:

• Clinical diagnosis of Erythema migrans

• Over the age of 18

• Signing an concent form after information in writing

Exclusion Criteria:

• Allergic to any of the three drugs in the study

• Under the age of 18

• Pregnancy

• Dementia or known drug abuse

• Antibiotic treatment last 14 days

• Concommitant Chemotherapy or immunomodulating therapy

• Concommitant use of medicine with potential interaction (defined in protocol)