Comparing Analgesic Efficacy of Systemic Lidocaine Against Placebo in General Anesthesia in Bariatric Surgery

• Status: Completed
• Trial end date: 2021-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators plan to evaluate the analgesic effect of systemic Lidocaine in addition to general anesthesia during bariatric surgery. Patients will be subdivided into a "Lidocaine group" and a "Control group".

The primary outcome will be the proportion of patients suffering from higher pain intensity within the first four hours after bariatric surgery.

Secondary outcomes include the average maximal pain intensity during first four hours and during 48 hours, total opiate consumption, occurence of postoperative nausea and vomiting, time to first defecation and total time spent in hospital.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Miodrag Filipovic, Prof. Dr. med.
• Treatments: Analgesics; Anesthetics; Lidocaine

Criteria

Inclusion Criteria:

• elective laparoscopic bariatric surgery

• ASA classification I - III

• age 18 - 80

• given informed consent

Exclusion Criteria:

• no written consent

• allergy to the investigational product

• cardiac arrhythmia (pacemaker)

• liver dysfunction (Child-Pugh classification A, B or C)

• pregnancy

• central nervous disease

• chronic pain and pre-existing opiate prescription

• expected non-compliance

• drug/alcohol abuse