Overview

Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial

Status:
Recruiting
Trial end date:
2024-10-01
Target enrollment:
Participant gender:
Summary
This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll. Eligible participants will be randomized to 1 of 2 groups of medications (Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) plus acetaminophen or low dose opioids plus acetaminophen). It is anticipated that the NSAID group will have superior clinical outcomes and fewer side effects when compared to the opioid group.
Phase:
Phase 4
Details
Lead Sponsor:
University of Michigan
Collaborator:
Patient-Centered Outcomes Research Institute
Treatments:
Acetaminophen