Comparing Different Regimens for Eradication of Helicobacter Pylori in Kuwait

• Status: Completed
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Eradication of H. pylori reduces morbidity in patients with chronic gastritis and can prevent gastric cancer. We aimed to evaluate the efficacy of clarithromycin-based triple therapy and non-bismuth based quadruple therapy for eradicating H. pylori in patients with chronic gastritis in Kuwait.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Al-Azhar University
• Collaborator: Ministry of Health, Kuwait
• Treatments: Amoxicillin; Clarithromycin; Metronidazole; Omeprazole

Criteria

Inclusion Criteria:

• Male and female dyspeptic subjects aged ≥18 years with any nationality

• Patients with gastric biopsy-proven H. pylori related chronic gastritis and no other abnormalities in the upper gastrointestinal tract upon endoscopy

• Patients who were naive to treatment for H. pylori infection.

Exclusion Criteria:

• Pregnant or breastfeeding females

• Patients who were previously treated for H. pylori infection

• Patients who received any antibiotics, bismuth or acid-suppressant drugs within the last month