Comparing Intra-articular Betamethasone (Diprospan) and Triamcinolone Acetonide Injection in Knee Osteoarthritis

• Status: Not yet recruiting
• Trial end date: 2023-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the efficacy of Intra-articular corticosteroid injection between Betamethasone (Diprospan) and Triamcinolone acetonide for treatment of knee osteoarthritis

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Thammasat University
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate; Triamcinolone; Triamcinolone Acetonide; Triamcinolone diacetate; Triamcinolone hexacetonide

Criteria

Inclusion Criteria:

1. Symptomatic Primary knee osteoarthritis (Kellgren-Lawrence stage 2 or 3)

2. Failed other conservative treatment

3. Comply with protocol

Exclusion Criteria:

1. Allergy to any of the medications in this protocol (Betamethasone, Triamcinolone, Paracetamol, Tramadol)

2. Previous fracture or surgical procedure

3. Previous intra-articular injection in the past 6 months

4. Previous oral Symptomatic slow-acting drugs for osteoarthritis (SYSADOA) (Glucosamine, Diacerein) used in the past 6 months

5. Current infection in the affected limb

6. Uncontrolled Diabetes Mellitus

7. Primary or secondary adrenal insufficiency

8. Coagulopathy or current anticoagulant used

9. Current steroid used

10. Lower extremity weakness