Comparing Reversal With Neostigmine and Sugammadex in Paediatric
Status:
Completed
Trial end date:
2016-06-30
Target enrollment:
Participant gender:
Summary
A reversal agent is commonly given to improve neuromuscular function after intra-operative
administration of non-depolarizing neuromuscular blocking agents. The administration of
conventional reversal agent neostigmine is associated with many undesirable side effects. For
almost a decade, a new novel drug sugammadex has been used to specifically antagonize the
effect of aminosteroidal neuromuscular blocking agents.
A total of 80 paediatric patients planned for general anaesthesia were divided into two
groups and were given either neostigmine+atropine, or sugammadex for reversal once the
operation had completed.
Phase:
N/A
Details
Lead Sponsor:
Universiti Sains Malaysia University of Science Malaysia