Comparing Single-dose Low-volume PEG Plus Bisacodyl vs. Split-dose PEG for Bowel Preparation in Morning Colonoscopy

• Status: Completed
• Trial end date: 2019-09-30
• Target enrollment: 0
• Participant gender: All

Summary

Colonoscopy is the best method to detect colorectal cancer and colonic polyps. Studies showed that adenoma detection rate positive correlation with good bowel preparation which makes bowel preparation an important issue. Hence, investigators conduct a clinical trial about adding another laxative agent to morning single dose low-volume PEG. To see if this new regimen could have non-inferior efficacy and lower life/sleep impact compared with standard regimen.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Taipei Medical University WanFang Hospital
• Treatments: Bisacodyl

Criteria

Inclusion Criteria:

• Age between 20-70 years.

• Out-patient department ambulatory patient.

• Patients who have indications to receive colonoscopy.

Exclusion Criteria:

• Age is under 20 or over 70

• Have severe renal impairment (hemodialysis or eGFR<30).

• Have severe congestive heart failure (NYHAⅢorⅣ).

• Pregnant or lactating, or women is under oral contraceptive.

• Have history of bowel obstruction or resection, known or suspected gastroparesis acute gastric/intestinal ulcer, toxic colitis or megacolon

• Be allergic to polyethylene glycol (PEG) or bisacodyl.

• Have severe constipation ( ≤ 1 bowel movement per week).

• Patient who has Phenylketonuria.

• Refuse to sign consent to the study.