Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection
Status:
Recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
Intratympanic steroid injections are an accepted treatment for Meniere's disease and
idiopathic sudden sensorineural hearing loss. This treatment is typically performed using
local topical anesthesia. There is very limited research on the differences of medications
and application procedures effect on patients' pain during the procedure.Topical Tetracaine
solution and topical phenol have been shown to be effective as local anesthesia for the
tympanic membrane when used for myringotomy. Currently there is no consensus on medication
and technique however focally applied phenol is the more widely used technique. We believe
this study can provide valuable information given the disadvantages of topical phenol
including burning upon application as well as possible increase in persistent tympanic
membrane perforation. The objectives are to determine the effectiveness of tetracaine drops
for local anesthesia for intratympanic steroid injections compared to focal topical phenol
application and to identify if tetracaine drops provides adequate anesthesia for
intratympanic steroid injection with less pain on application than focal phenol.
Phase:
Early Phase 1
Details
Lead Sponsor:
Our Lady of the Lake Hospital
Collaborator:
Louisiana State University Health Sciences Center - New Orleans