Comparing Two Regimens for Medical Abortion: Mifepristone+Misoprostol Versus Misoprostol Alone
Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
A double blinded, placebo-controlled randomized trial to compare the safety, efficacy and
acceptability of two medical abortion regimens up to 63 days' LMP. The first regimen will
include a 200 mg oral dose of mifepristone followed by 800 mcg buccal misoprostol. The second
regimen will include two 800 mcg doses of buccal misoprostol. We hypthesize that both methods
work well, but that the mifepristone regimen will have an efficacy rate of approximately 95%,
and misoprostol alone will be closer to 90%. We will consider a greater than 5% difference to
be clinically meaningful.