Comparing the Efficacy of Anti-secretory Versus Oral Immunoglobulins for Reducing the Episodes of Diarrhea in Children

• Status: Not yet recruiting
• Trial end date: 2022-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Children 1-12 years presenting/admitted with acute diarrhea will be enrolled in the study after taking informed consent from the parents. Patients will be randomly allocated to two equal groups. Group A (GA) will receive anti secretory 1.5mg/kg/dose, three doses in 24 hours along with oral rehydration, while Group B (GB) will receive a single dose of bovine immunoglobulins. Response to treatment will be assessed by recording the frequency of loose stools after 72 hrs. Data will be collected through a structured proforma.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University
• Treatments: Racecadotril

Criteria

Inclusion Criteria:

• Children 1-12 years both male and female visiting/admitted in Children Hospital PIMS with acute diarrhea of less than 15 days duration

Exclusion Criteria:

• Children requiring emergency resuscitation.

• Children having diarrhea of more than 15 days duration..

• Children with other comorbid conditions like heart, kidney and liver failure.

• Children with fructose intolerance, glucose malabsorption syndrome and saccharase isomaltase deficiency.

• Children allergic to egg or any of the contents.