Comparision of Motor Seizure Duration of Ketofol and Propofol for Electroconvulsive Therapy

• Status: Completed
• Trial end date: 2021-06-15
• Target enrollment: 0
• Participant gender: All

Summary

Propofol is routinely used in our hospital for ECT. It causes hypotension and has anticonvulsant actions. Use of ketofol ( 1:1 combination of ketamine and propofol) during ECT can have longer seizure duration and better hemodynamics than propofol alone which ultimately leads to better therapeutic efficacy. Motor seizure duration of minimum 20-25 seconds is usually recommended for therapeutic efficacy of ECT.Patients planned for electroconvulsive therapy meeting the inclusion criteria and not having exclusion criteria will be randomized into two groups. Group K will receive titrated dose of Ketofol and Group P will receive titrated dose of Propofol for induction of anaesthesia

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Tribhuvan University Teaching Hospital, Institute Of Medicine.
• Treatments: Propofol

Criteria

Inclusion Criteria:

• • All patients scheduled for electroconvulsive therapy irrespective of ECT sessions.

• Patients between 16 to 65 years of age

• Patients with ASA -PS of I and II

Exclus• Pregnant patients

• Patients with a history of Epilepsy

• Patients taking any anticonvulsant medication

• Patients with a history of substance abuse or dependence

• Patients with a history of any adverse effect to any drugs used during the procedure

ion Criteria:

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