Comparison Azathioprine to Mesalazine for the Prevention of Postoperative Recurrence in the Crohn Disease

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To show the superiority of Azathioprine comparing Mesalazine in the prevention of postoperative recurrence in Crohn's Disease.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives
• Treatments: Azathioprine; Mesalamine

Criteria

Inclusion Criteria:

• more than 18 years old

• Clinical remission at inclusion time (CDAI<150)

• Having ileocolonic or colon resection 21 days before inclusion

• Resection > 50cm or subtotal colectomy with ileorectal anastomosis

Exclusion Criteria:

• Intolerance to one of both study treatment

• Liver failure (TP<60%)

• Renal Failure (Creatinine < Lab results)