Comparison Between Budesonide and Dexamethasone Treatments for Respiratory Discomfort After Extubation on Children

• Status: Unknown status
• Trial end date: 2016-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The study aims to analyze and compare the clinical effects of using inhaled budesonide or intravenous dexamethasone in the treatment of postextubation stridor on children admitted to the pediatric intensive care units at Hospital Municipal do M´Boi Mirim and Hospital Albert Einstein.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Israelita Albert Einstein
• Collaborator: Hospital M'Boi Mirim
• Treatments: BB 1101; Budesonide; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate

Criteria

Inclusion Criteria:

• patients intubated for periods longer than 24hs

• age between 28 days and than 15 years

• post extubation stridor must be clinically diagnosticated by a MD

• informed consent must be obtained

Exclusion Criteria:

• patients under palliative care

• presence of neuromuscular disease

• previous airway pathologies

• epiglottitis, aspiration of foreign bodies

• viral laryngitis

• former airway surgery

• patients previously included in the study within the same hospital admission

• corticosteroid use in the 48hs preceding extubation