Comparison Between Histidine-tryptophan-ketoglutarate Cardioplegia and Cold Blood Cardioplegia for Myocardial Protection for Fallot Tetralogy Patients Undergoing Total Repair

• Status: Recruiting
• Trial end date: 2022-03-15
• Target enrollment: 0
• Participant gender: All

Summary

Randomized clinical trial: comparison between Histidine-tryptophan-ketoglutarate cardioplegia and cold blood cardioplegia for myocardial protection for Fallot tetralogy patients undergoing total repair This study aims to compare HTK cardioplegic solution and cold blood cardioplegia to provide optimal myocardial protection for a patient with tetralogy of Fallot planned for total repair.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University

Criteria

Inclusion Criteria:

• Pediatric patients with tetralogy of Fallot spectrum.

• Sex (males and females)

• Age 6 months- 5 years.

Exclusion Criteria:

• Persistent left SVC draining in the coronary sinus.

• Mental or neurologic disorders.

• Preoperative critically ill patients.

• Parents or legal guardian refusal.

• Fallot repair with transannular patch( as it will affect on the RV function as a single agent after reperfusion)