Comparison Between Long-pulsed Nd:YAG, Amorolfine and Combination Treatment in Treating Non-dermatophyte Onychomycosis

• Status: Completed
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to compare the efficacy and safety of amorolfine, long-pulsed Nd:YAG laser and the combination between amorolfine and long-pulsed Nd:YAG in treating the non-dermatophyte and mixed-infection onychomycosis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mahidol University
• Treatments: Amorolfine

Criteria

Inclusion Criteria:

1. The patients aged more than 18 years old.

2. The patients were diagnosed with non-dermatophytes or mixed-infection onychomycosis from both KOH examination and fungal cultured.

3. The patients did not have any prior anti-fungal treatment within 6 months

4. The patients did not receive any vasodilator drugs or isotretinoin within 6 months

5. The patients who are willing to participate, and accept the methods and risk

Exclusion Criteria:

1. The patients who suffered other medical dermatologic condition associated with onychomycosis such as psoriasis, paronychia etc.

2. The patients who took immunosuppressive drugs, or the immunocompromised host.

3. The patients who had severe vascular disease, such as severe DVT, or poor capillary refill time.

4. The patients who had onychomycosis which involved in nail matrix.

5. Pregnancy or lactation.

6. The patients who had problems communication or have difficulty travel to the faculty for the checkup.