Comparison Between Nurse-Administered Propofol Sedation and Diazemuls / Pethidine in Outpatient Colonoscopy
Status:
Completed
Trial end date:
2006-06-01
Target enrollment:
Participant gender:
Summary
Colonoscopy is a common endoscopic procedure as an investigation of colorectal pathology.
Different modalities of pain control have been described in the past. Propofol is a perfect
drug for endoscopic procedure since it has the characteristic of fast onset, short half-life
and early recovery. Its unfamiliarity and its potential cardiovascular and respiratory side
effect make it unpopular to endoscopists. Recent reports showed propofol is safe in bolus
titration by nurse in Caucasian in all endoscopic procedures. Our previous pilot study showed
nurse administered propofol sedation (NAPS) is effective and safe and highly acceptable by
Chinese patients. Here we conduct a randomized controlled study to compare the effectiveness
of NAPS versus traditional sedation.