Comparison Between Platelet Rich Plasma and Corticosteroids for the Treatment of Rotator Cuff Tendinopathy

• Status: Completed
• Trial end date: 2023-08-31
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to test if Plateth-rich plasma would provide improved pain relief and function in patients with rotator cuff tendinopathy compared to standard treatment of corticosterone injections.

Researchers will compare a control group of patients treated with a corticosterone injection with a case group of patients treated with Plateth-rich plasma injection.

The purpose of this study is to perform a double-blind randomized controlled trial, comparing PRP with corticosteroids to provide pain relief and improve function in patients with rotator cuff tendinopathy. The hypothesis of this study is that PRP would provide improved pain relief and function in patients with rotator cuff tendinopathy compared to standard treatment of CS injections.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Italiano de Buenos Aires

Criteria

Inclusion Criteria:

• symptomatic rotator cuff tendinopathy (confirmed by ultrasound).

• At least 3 months of failed conservative treatment (decreased activity, anti-inflammatories, kinesiology for at least 3 months before diagnosis).

Exclusion Criteria:

• Refusal to participate or informed consent

• Previous shoulder surgery,

• Partial or total tears of the rotator cuff,

• Patients with shoulder osteoarthritis

• Advanced fatty infiltration of the rotator cuff muscles

• Systemic or rheumatoid arthritis,

• Uncontrolled diabetes,

• Acute or chronic infections of the shoulder to be operated on

• Ongoing cancer chemotherapy therapies

• Sepsis, septic arthritis, osteomyelitis or other ongoing infectious processes;

• Patients with autoimmune diseases;

• Pregnants