Comparison Between Thrombolysis and Primary Percutaneous Coronary Intervention (PCI) to Treat ST-Segment Elevation Myocardial Infarction

• Status: Completed
• Trial end date: 2004-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The main objective is to compare a fibrinolytic strategy with an interventional strategy initiated as early as possible, preferably in the pre-hospital phase, with respect to resolution of ST-segment elevation at 120 minutes after inclusion and Thrombolysis In Myocardial Infarction (TIMI) flow grade evaluated at a mandated coronary angiography 5 to 7 days after inclusion.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sahlgrenska University Hospital, Sweden
• Collaborators: Norra Alvsborgs Lans Hospital, Trollhattan; Region Örebro County; Stockholm South General Hospital; Varberg Hospital, Sweden
• Treatments: Abciximab; Dalteparin; Heparin, Low-Molecular-Weight; Reteplase

Criteria

Inclusion Criteria:

• Patients presenting within 6 h after onset of chest pain lasting for more than 30 min and with significant ST-segment elevation on ECG.

Exclusion Criteria:

• BP >180/110

• Known bleeding disorder

• Cardiogenic shock

• CPR>10 min

• Ongoing anticoagulant therapy

• Renal insufficiency

• Weight >120 kg