Overview

Comparison Between a 1L of Polyethylene Glycol+Ascorbic Acid as a Split Dose Bowel Preparation for Colonoscopy

Status:
Recruiting
Trial end date:
2021-12-31
Target enrollment:
0
Participant gender:
All
Summary
Comparison between a 1L of polyethylene glycol+ascorbic acid as a split dose and oral sulfate solution bowel preparation for colonoscopy study design: prospective, randomized, parallel, multi-center trial in 3 hospitals in Korea ( Seoul National University hospital, Seoul National University Bundang hospital, Seoul Metropolitan Government-Seoul National University ) patient inclusion criteria - aged 20-75 adults (out-clinic patients) scheduled for colonoscopy for any indication within the normal process of care
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Seoul National University Hospital
Criteria
Inclusion Criteria:

- Adult out clinic patients scheduled for colonoscopy for any indication within the
normal process of care

Exclusion Criteria:

- previous history of significant gastrointestinal surgeries (except for appendectomy)

- known or clinically suspicious Inflammatory bowel disease patients

- known or suspected ileus/ GI obstruction

- previous history of major cancer or currently on treating cancer

- Major cardiovascular disease, respiratory disease, liver, hematologic diseases with
complication

- severe cognitive impairment / dementia / confusion state

- past history within the last 12 months or current episode of severe constipation
severe constipation

- Regular use of laxatives or colon motility-altering drugs (i. e. more than 2 - 3 times
per week) in the last 28 days prior to screening and/or laxative use within 72 hours
prior to administration of the preparation)

- women who are pregnant or lactating

- known phenylketonuria, glucose-6-phosphate dehydrogenase deficiency

- those who were allergic to any preparation components.

- those who, in the opinion of the investigator, should not be included in the study for
any reason