Comparison Of Dexmedetomidine and Fentanyl In Attenuation Of Hemodynamic Response To Direct Laryngoscopy And Intubation In Patient Undergoing Laparoscopic Cholecystectomy.

• Status: Completed
• Trial end date: 2019-07-15
• Target enrollment: 0
• Participant gender: All

Summary

Compare effects of intravenous dexmedetomidine and fentanyl in attenuation of intubation response in a patient undergoing laparoscopic cholecystectomy.

Compare the effects of intravenous dexmedetomidine and fentanyl in sedation, perioperative complications, and recovery in these patients.

Dexmedetomidine is comparatively a newer drug in countries like Pakistan. There is no research work available at the national level and scarcity of data at an international level with inconclusive outcomes. Our participation in the form of this research will add to scientific literature and step up ahead at the international level.

Fentanyl citrate is a narcotic analgesic interacting predominantly with the opioid μ receptor and exerting its principal pharmacological effect on CNS. Its primary action of therapeutic value is analgesia and sedation. It is extensively used for anesthetic and analgesic most often in operating room and ICU.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dow University of Health Sciences
• Treatments: Dexmedetomidine; Fentanyl

Criteria

Inclusion Criteria:

1. ASA-I and ll patients

2. Male and female patient of age 20-70 years.

3. Undergoing Elective laparoscopic cholecystectomy.

Exclusion Criteria:

1. Pregnant and lactating females

2. Short thick neck with anticipated difficult intubation.

3. Obese patients.

4. Narcotic addicts.

5. Full stomach patient or with higher chances of aspiration.

6. Patient allergic to any of the study medications.

7. Patients high risk to develop serotonin syndrome. (patient taking an antidepressant and other psychomotor medications.