Comparison Study of EAP and CG Regimens for Mobilizing Hematopoietic Stem Cells in Multiple Myeloma Patients
Status:
RECRUITING
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
This is a prospective, randomized, two-arm, multicenter, exploratory study aimed at evaluating the efficacy and safety of the combination of etoposide, cytarabine and Pegfilgrastim (EAP regimen) for mobilizing hematopoietic stem cells in patients with newly diagnosed multiple myeloma (NDMM). A total of 99 NDMM patients will be enrolled and randomly assigned to receive either the EAP regimen or the GC regimen (cyclophosphamide+ G-CSF) to mobilize hematopoietic stem cells. Subsequently, the mobilization effects and adverse reactions of all patients will be observed and compared.
Phase:
PHASE3
Details
Lead Sponsor:
The Affiliated People's Hospital of Ningbo University
Collaborators:
Affiliated Hospital of Jiaxing University Dongyang People's Hospital First Affiliated Hospital of Wenzhou Medical University First Affiliated Hospital of Zhejiang University Huizhou Municipal Central Hospital Jinhua Municipal Central Hospital Jinhua People's Hospital Ningbo Medical Center Lihuili Hospital Second Affiliated Hospital of Wenzhou Medical University Shaoxing People's Hospital Shaoxing Second Hospital Taizhou Hospital Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University The Central Hospital of Lishui City Zhejiang Provincial Tongde Hospital