Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Carbonated Drink

• Status: Completed
• Trial end date: 2018-12-05
• Target enrollment: 0
• Participant gender: All

Summary

The diurnal variation in the flow of saliva and hence the composition of saliva is an established fact. Consumption of acidic and sweetened food and beverage is known to reduce the salivary pH and some of them reduce it to critical pH levels and result in structural damage to the hard tissues of the tooth.

The purpose of this study is to ascertain the effect of the select commercially available test carbonated drink containing sugar on the salivary pH and assess the buffering capacity of the saliva with or without various intervention measures following the exposure to the test carbonated drink at different time intervals.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Dr Meru S
• Treatments: Chlorhexidine; Chlorhexidine gluconate; Listerine; Pharmaceutical Solutions; Sodium Fluoride

Criteria

Inclusion Criteria:

• subjects in the age group of 18 to 30 years.

• subjects with a DMFT index score of less than 2.

• subjects with Loe and Silness index score of 0.

• subjects willing to volunteer for the study.

• subjects who are available for the whole study period of 4 months.

Exclusion Criteria:

• subjects with history of gastritis and bulimia.

• subjects with chronic medical illness.

• subjects with history of allergy.

• subjects with history of drug intake for last 8 weeks.

• subjects who smoke or chew tobacco.