Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial

• Status: Recruiting
• Trial end date: 2023-01-05
• Target enrollment: 0
• Participant gender: Male

Summary

The investigators aim is to conduct a double blind randomized clinical trial, to study the effects of Acetyl-L-Carnitine and folic acid versus Coenzyme Q10 and folic acid on Semen and hormonal parameters and semen oxidative stress in patients of Primary infertility. Males diagnosed with Primary Infertility are recruited in the study after fulfilling the inclusion nd exclusion criteria. The investigators propose that Primary infertile men may have altered seminal oxidative status & the combinational therapy may achieve favorable seminal , hormonal& antioxidant levels in men having Primary infertility.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Khyber Medical University Peshawar
• Treatments: Acetylcarnitine; Folic Acid

Criteria

Inclusion Criteria:

1. Treatment naïve primary male infertile patients with Oligospermia, Asthenozoospermia , Teratozoospermia & Necrozoospermia

2. Aged between 20 - 45 years

3. Married for more than a year with regular intercourse minimum 3/week.

4. Normal female partner with normal menstrual cycle

Exclusion Criteria:

1. Azoospermic patients

2. Patients with varicocoele

3. Erectile dysfunction

4. Secondary infertility

5. Patients already taking treatment for primary infertility