Comparison of Aerosol Inhalation and Intravenous Glucocorticoid in the Treatment of Severe AECOPD

• Status: Enrolling by invitation
• Trial end date: 2025-07-31
• Target enrollment: 0
• Participant gender: All

Summary

Comparison of aerosol inhalation and intravenous glucocorticoid in the treatment of severe AECOPD-------Multicenter, prospective, randomized, controlled clinical study

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dong Yang
• Collaborator: Jilin University
• Treatments: Glucocorticoids

Criteria

Inclusion Criteria:

(1) Patients with AECOPD requiring hospitalization or emergency treatment (COPD acute attacks combined with respiratory failure were eligible). (2) 18 years of age ≤80 years of age (3) Patients and their families are willing to participate in clinical research and sign informed consent.

Exclusion Criteria:

1. Combined with tuberculosis.

2. Combined bronchiectasis.

3. complicated with definite infectious diseases.

4. PCT≥0.5ng/ml or CRP≥30mg/L.

5. Serious injury combined with other organ functions

6. Contraindications to other glucocorticoid use.

7. Concomitant bronchial asthma or positive bronchodilation test