Comparison of Biocompatibility of Plasmapheresis Procedures With Citrate and Heparin Anticoagulation
Status:
Recruiting
Trial end date:
2022-12-30
Target enrollment:
Participant gender:
Summary
Membrane plasmapheresis is one of the methods for treating immune diseases. Plasmapheresis
removes autoantibodies and immune complexes, paraproteins, lipoproteins and reduces the
concentration of cytokines. In membrane plasmapheresis, plasma is separated from blood cells
by a highly permeable membrane. The filtered plasma is then discarded and replaced with
replacement fluid. During the procedure, there is an activation of the coagulation system,
because of the extracorporeal blood circulation. The anticoagulation during the procedure is
therefore necessary.