Comparison of Brain Perfusion in Rhythm Control and Rate Control of Persistent Atrial Fibrillation
Status:
Unknown status
Trial end date:
2020-11-01
Target enrollment:
Participant gender:
Summary
Atrial fibrillation (AF) is associated with impaired cognitive function (CogF) and/or
dementia, but it is unclear whether rhythm control of AF improves CogF or brain perfusion.
The hypothesis is rhythm control of AF improves CogF by increasing brain perfusion with
hemodynamic amelioration compared to AF state. We will randomize the patients with persistent
AF to rhythm control group and rate control group, and check baseline and 3rd month cognitive
function (K-MOCA score) and brain perfusion CT. K-MOCA score and brain perfusion CT findings
will be compared between rhythm control group and rate control group of persistent AF.