Comparison of Caffeine Reduction and Anticholinergic Medications for Treatment of Overactive Bladder

• Status: Terminated
• Trial end date: 2013-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to assess the effects of caffeine reduction/elimination on urinary symptoms in women with overactive bladders and compare this therapeutic approach to anticholinergic therapy. We hope to show a reduction in symptoms with caffeine reduction and determine how effective caffeine reduction is compared to medication. If caffeine reduction is shown to be beneficial, women may be encouraged to use this strategy before resorting to medications.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: IWK Health Centre
• Treatments: Caffeine; Cholinergic Antagonists

Criteria

Inclusion Criteria:

1. Women with OAB symptoms including urgency, frequency (voids ≥8/day), and urge incontinence

2. Women who consume > one cup (250ml) caffeinated beverage per day

3. Women who score $ 6 on the QUID Questionnaire for urgency symptoms

Exclusion Criteria:

1. Women currently receiving treatment for OAB symptoms

2. Women with narrow angle Glaucoma

3. Women taking anticholinergics or loop diuretics

4. Women with an untreated urinary tract infection. After resolution of the UTI, and if all other eligibility criteria are met, the woman can be a candidate for inclusion in the study.

5. Women with a diagnosis of painful bladder syndrome or other abnormal urinary tract lesions

6. Women scoring >4 on the QUID Questionnaire for stress symptoms

7. Women with de novo symptoms following surgery

8. Women with major pelvic prolapse