Comparison of Cefdinir and Cefdinir/Clavulanic Acid Combination in Adults

• Status: Unknown status
• Trial end date: 2018-08-01
• Target enrollment: 0
• Participant gender: All

Summary

It is planned to compare the efficacy and safety of cefdinir and cefdinir/clavulanic acide treatments in acute exacerbation of chronic bronchitis (AECB) and community-acquired pneumoniae (CAP) patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Neutec Ar-Ge San ve Tic A.Ş
• Treatments: Cefdinir; Cephalosporins; Clavulanic Acid; Clavulanic Acids

Criteria

Inclusion Criteria:

• The diagnosis of chronic bronchitis

• The diagnosis of community-acquired pneumoniae

• FEV1 value = 30-80%

• The diagnosis of mild-severe acute exacerbation of chronic bronchitis (AECB)

• Oxygen saturation < 90%

Exclusion Criteria:

• Pregnancy or breastfeeding

• Allergy against to penicillin or cephalosporins

• Renal impairment

• Active hepatic disease

• Antibiotic use except study drugs

• Immunosuppressive therapy before 6 months of study initiation

• Use of probenecid like drugs