Comparison of Clopidogrel Versus Ticagrelor Therapy for Atherosclerotic Plaque Inflammation
Status:
Completed
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
Objectives: To compare the effects of clopidogrel versus ticagrelor on atherosclerotic plaque
inflammation using serial FDG PET/CT imaging of carotid artery and ascending aorta.
Hypothesis: Thrombosis and inflammation are tightly linked rather than separate entities.
Therefore, P2Y12 receptor inhibitors may have an anti-ischemic effect by inhibiting plaque
inflammation, and ticagrelor may be superior in efficacy to clopidogrel.
Phase:
Phase 4
Details
Lead Sponsor:
CHEOL WHAN LEE, M.D., Ph.D
Collaborators:
AstraZeneca CardioVascular Research Foundation, Korea