Comparison of Dexmedetomidine and Meperidine for the Prevention of Shivering Following Coronary Artery Bypass Graft

• Status: Not yet recruiting
• Trial end date: 2022-08-31
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to explore the effectiveness and safety of dexmedetomidine for the prevention of postoperative shivering in the patients undergo elective coronary artery bypass graft, and to compare the effectiveness of dexmedetomidine and meperidine on the incidence of shivering in the patients undergo coronary artery bypass graft.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Qianfoshan Hospital
• Treatments: Dexmedetomidine; Meperidine

Criteria

Inclusion Criteria:

1. patients older than 18 years and younger than 75 years;

2. patients undergo elective coronary artery bypass graft；

3. ASA II-IV grade；

4. In accordance with ethics, patients voluntarily participated in the trial and signed the informed consent for the clinical study;

Exclusion Criteria:

1. preoperative patients with neurological or psychiatric disorders;

2. preoperative hepatic and renal insufficiency;

3. severe hyperthyroidism or hypothyroidism;

4. The temperature of patients greater than 38℃ or less than 36℃;

5. postoperative hemodynamic instability;

6. preoperative use of left ventricular auxiliary equipment;

7. Patients with severe diabetic complications (diabetic ketoacidosis, hyperosmolar coma, various infections, diabetic nephropathy);

8. Patients who have participated in other clinical studies within 3 months;