Comparison of Dexmedetomidine and Midazolam for Prevention of Emergence Delirium in Children

• Status: Completed
• Trial end date: 2018-12-17
• Target enrollment: 0
• Participant gender: All

Summary

Emergence delirium is a common complication in children after anesthesia. The incidence of emergence delirium is reported upto 50%. Prevention of emergence delirium in children is important not only for the patient safety but also for the satisfaction of the parents. Midazolam is the most commonly used medications for prevention of emergence delirium. However, it might lead to delayed awakening from anesthesia and respiratory depression. In this study, the investigators will evaluate whether dexmedetomidine can be effectively and safely administered for prevention of emergence delirium in children compared to midazolam.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Eunah Cho, MD
• Treatments: Dexmedetomidine; Midazolam

Criteria

Inclusion Criteria:

• Patients undergoing elective tonsillectomy under general anesthesia

• American society of anesthesiologist physical status 1,2

• aged from 24 months to 12 years old

• obtaining written informed consent

Exclusion Criteria:

• known history of allergy to dexmedetomidine or midazolam

• renal impairment

• hepatic impairment

• long QT syndrome

• developmental disorder

• congenital disorder

• neurologic disorder

• psychogenic disorder