Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity

• Status: Unknown status
• Trial end date: 2018-12-20
• Target enrollment: 0
• Participant gender: All

Summary

This is a single center, randomized control. Sixty eligible subjects will be recruited into 3 study treatment groups (n=20 per group) through computerized randomization. Subjects in group 1 will be treated with 8% arginine containing paste(Colgate® Sensitive Pro-Relief™), group 2 with 5% topical fluoride varnish (Acclean) and group 3 with self-adhesive resin (Seal and protect, Dentsply). The subjects in the study will be evaluated for tactile and air-blast hypersensitivity criteria at baseline, two and four weeks.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aga Khan University
• Treatments: Fluorides; Fluorides, Topical

Criteria

Inclusion Criteria:

• Patients with age 18 and above with dentine hypersensitivity will be selected.

• At least two hypersensitive teeth which will be sensitive to air blast (Schiff air sensitivity scores of 2 or 3) and positive tactile sensitivity assessed clinically with explorer

• Written informed consent (and assent when applicable) obtained from subject or subject's legal representative and ability for subject to comply with the requirements of the study.

Exclusion Criteria:

• • Patients who would have undergone any periodontal procedure or gotten any professionally applied desensitizers in the last three months.

• Patients having generalized sensitivity in all teeth

• Chronic use of anti-inflammatory and analgesic medications

• Pregnant or lactating females;

• Any denture bridgework; active cervical caries or deep abrasion requiring Class V fillings;

• Fractured, crowned or root filled teeth and teeth with large restorations

• Carious teeth or cracked teeth assessed on the basis of clinical judgment