Comparison of Dosimetry After rhTSH or Withdrawal of Thyroid Hormone in Metastatic or Locally Advanced Thyroid Cancer
Status:
Terminated
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Metastases of thyroid cancer with iodine uptake are treated with repeated activity of I-131
administered after thyroid hormone withdrawal. The goal of thyroid hormone withdrawal is to
treat patients with elevated thyrotropin stimulated hormone (TSH), a hormone secreted by the
pituitary, a gland just located under the brain. Another way to obtain elevated TSH levels is
to perform intramuscular injection of recombinant human TSH, a hormone produced
pharmaceutically. The goal of this study is to know whether the radioiodine uptake by the
metastases is similar after rhTSH administration or after thyroid hormone withdrawal.