Comparison of Effects Between Amlodipine and Hydrochlorothiazide in Combination With Losartan on 24-hr Central Blood Pressure in Hypertensive Patients

• Status: Completed
• Trial end date: 2016-05-18
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate which combination therapy is more effective for improving the blood pressure (BP) and AM central SBP in hypertensive patients:Angiotensin II receptor blocker (ARB) plus calcium channel blocker (CCB) or ARB plus diuretics

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chong-Jin Kim
• Collaborator: Hanmi Pharmaceutical Company Limited
• Treatments: Amlodipine; Angiotensin Receptor Antagonists; Calcium Channel Blockers; Hydrochlorothiazide; Losartan

Criteria

Inclusion Criteria:

• Hypertension patients not included exclusion criteria

• Mean seated SBP ≥140mmHg in patients with newly Diagnosed

Exclusion Criteria:

• msDBP≥110mmHg or ms SBP ≥ 180mmHg at the screening and randomization visit