Comparison of Efficacy Dimenhydrinate and Metoclopramide in the Treatment of Nausea Due to Vertigo

• Status: Completed
• Trial end date: 2013-05-01
• Target enrollment: 0
• Participant gender: All

Summary

• Vertigo complaint is one of the common cause of patients who applied to emergency services.

• Patients who have applied to emergency services with vertigo complaint mostly have nausea as an additionally symptom to this complaint and anti-emetic agents can be used in their treatments very often.

• The investigators purpose is to investigate the advantages of Dimenhydrinate and metoclopramide to each other in the treatment of vertigo and the vertigo accompanied by nausea

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pamukkale University
• Treatments: Dimenhydrinate; Metoclopramide

Criteria

Inclusion Criteria:

• between 18 to 65 years old patients,

• had vertigo and accompanied nausea or vomiting [VAS (visual analog scale) score >5] during their emergency department episode of care for which the attending physician recommended intravenous antiemetic medication.

Exclusion Criteria:

• abnormal vital signs,

• women who were pregnant or lactation,

• those with a history of epilepsy,

• acute psychiatric symptoms,

• organic brain disease,

• parkinson's disease or phaeochromocytoma,

• or any known allergy to the study drugs,

• uncooperative individuals,

• use of any antiemetic drug in the previous 8 hours or previous delivery of intravenous fluids during the emergency department episode of care,

• currently undergoing chemotherapy or radiotherapy,

• mechanical obstruction or perforation,

• gastrointestinal bleeding,

• inability to understand study explanation or outcome measures (any reason),

• known allergy or previous adverse reaction to metoclopramide or dimenhydrinate,

• and patients who refused to participate study.