Comparison of Efficacy of Single Oral Dose Fluconazole and Itraconazole in Patients With Pityriasis Versicolor

• Status: Completed
• Trial end date: 2022-09-30
• Target enrollment: 0
• Participant gender: All

Summary

Pityriasis versicolor (PV) also called tinea versicolor is a common superficial chronic fungal infection of the skin caused by species of lipophilic yeast known as Malassezia species. Itraconazole is an oral synthetic triazole while fluconazole is an oral synthetic bis-triazole compound. Only a few studies are available to find a direct comparison of the efficacy of single dose of oral fluconazole (400 mg) and oral itraconazole (1000 mg) in the treatment of PV. The objective of the study was to compare the efficacy of single dose fluconazole (400 mg stat) to single dose itraconazole (1000 mg stat) in the treatment of pityriasis versicolor in the local population of Pakistan.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Combined Military Hospital Abbottabad
• Treatments: Fluconazole; Itraconazole

Criteria

Inclusion Criteria:

• All the patients above 18 years of age

• Diagnosed with pityriasis versicolor

Exclusion Criteria:

• Those patients who had received any antifungal treatment during last 1 month

• pregnancy

• lactation

• history of renal disease hepatic disease or malignancy

• history of hepatic disease

• history of malignancy